AMG 757 Studie A study to assess the safety, tolerability, and pharmacokinetics of AMG 757 in Subjects with Small Cell Lung Cancer (Aktiv)
Encephalon Whole Brain Radiation Therapy Alone vs. Radiosurgery for SCLC Patients With 1-10 Brain Metastases (ENCEPHALON) (Aktiv)
Erstlinie
AMG 20200469 A Phase 1b Study Evaluating the Safety and Efficacy of First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (Aktiv)
CRISP Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma Patients (Aktiv)
IMforte A Phase III, randomized, open-label, multicenter study of Lurbinectedin in combination with Atezolizumab compared with Atezolizumab as maintanence therapy in participants with extensive - stage SCLC following first-line induction therapy with carboplatin, Etoposid and Atezolizumab (Aktiv)
SPACE Patients With ES-SCLC and ECOG PS=2 Receiving Atezolizumab-Carboplatin-Etoposide (Aktiv)
TREASURE Thoracic RadiothErapy with Atezolizumab in Small cell lUng canceR Extensive disease (Aktiv)
Zweitlinie oder später
20200491 DeLLphi Eine Phase-2-Studie zur Beurteilung der Wirksamkeit, Sicherheit, Verträglichkeit und Pharmakokinetik von AMG 757 bei Patienten mit rezidiviertem/refraktärem kleinzelligem Lungenkarzinom nach mindestens zwei vorangegangenen Therapielinien (Aktiv)
BIOLUMA trial of nivolumab in combination with ipilimumab to evaluate efficacy and safety in relapsed lung cancer (Aktiv)
DLL3 A Study to Test Different Doses of BI 764532 in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for Delta-Like Ligand 3 (DLL3). (Aktiv)
SORATRAM Multizentrische Basket-Studie zur kombinierten CRAF- und MEK-Inhibition bei fortgeschrittenen Tumorerkrankungen mit BRAF-Mutationen und eingeschränkter Kinase-Aktivität (Aktiv)