GO42273 This study will evaluate the safety, pharmacokinetics, and activity of belvarafenib as a single agent and in combination with either cobimetinib or cobimetinib plus nivolumab in patients with NRAS-mutant advanced melanoma who have received anti-PD-1/PD-L1 therapy. (Aktiv)
MONETTE A Randomised, Open-Label, Phase 2 Study of Ceralasertib Monotherapy and Ceralasertib plus Durvalumab in Patients with Unresectable or Advanced Melanoma and Primary or Secondary Resistance to PD-(L)1 Inhibition Advanced Melanoma (Aktiv)
OMNIA-1 (ANV419-10) A Phase 1/2 Study of ANV419 as Monotherapy or in Combination With Anti PD1 or Anti-CTLA-4 Antibody Following Anti PD1/Anti-PDL1 Antibody Treatment in Patients With Unresectable or Metastatic Cutaneous Melanoma (Aktiv)